Woman loses ability to move legs after ‘nangs’ nitrous oxide overdose - NZ Herald (2024)

Claudia is learning to walk again after overdosing on nitrous oxide. Photo / Rayssa Almeida, RNZ

By RNZ

An Auckland woman who lost movement in her legs after inhaling nitrous oxide is urging the Government to regulate retail supply of the gas.

Known on the streets as nangs or laughing gas, nitrous oxide has been used as a sedative for pain relief for more than 150 years, but it has also been used as a recreational drug.

Auckland resident Claudia*, 24, was using nitrous oxide to numb the pain of a back injury.

“I broke my tailbone two years ago ... [I’ve] been in hospital many times, [but] they never helped.

“One night, my friend [inhaled nitrous oxide], and then I did it, too. Then I thought ‘Hey, it helps with the pain’.”

But what she was using for pain quickly became a habit.

“I wasn’t using [nitrous oxide] every day, it would be every couple of days.

“But the day that I did do it, I’d be consuming a lot, way too much.”

Claudia was consuming extra-large bottles of nitrous oxide, with up to 2 litres of gas.

Sold through dairies but legal

Nitrous oxide is normally sold to registered dentists and doctors as a pain relief. However, the gas can also be used as a propellant to make whipped cream and is sold nationally in dairies.

Claudia had access to the bottles through dairies in the city centre.

“I went to the point where ... I wasn’t getting anything out of it. I was just doing it and I didn’t get the normal fun effects from it or anything.

“One day, the police found me passed out in my car, but they said they couldn’t do much about it, because it was considered self-harm.”

In May, she ended up in hospital after losing movement in her legs.

“I woke up one morning and said ‘Mum, my hands and my feet are tingly’. Then I woke up the next day and couldn’t walk or use my hands.

“I tried to stand up, but then I fell over.”

In New Zealand, it is legal to sell canisters for food preparation purposes, but selling for inhalation can lead to up to six months of jail time or a $40,000 fine.

The retail supply of the gas is banned in the United Kingdom, with users facing up to two years in prison and dealers up to 14 years.

In Western Australia, from the second half of 2024, nitrous oxide canisters will only be accessible to registered food and beverage businesses.

‘It shouldn’t be that easy’ to buy - Claudia’s mother

Claudia’s mother, Merine Le Sueur, said easy access to the gas needed to be addressed.

“I went to the shop the other day to buy hair toner and I got asked for a hairdresser license. Why can’t there not be rules around anyone going to buy this product? It shouldn’t be that easy for us to just walk in and purchase this.

“People are, literally, not walking because of it. They are using it without understanding and being educated on its consequences. Who is going to care for those people?”

Currently in a rehabilitation centre trying to walk again, Claudia urged people to be aware of the consequences of the recreational use of nitrous oxide.

Woman loses ability to move legs after ‘nangs’ nitrous oxide overdose - NZ Herald (1)

“Do you want to end up paralysed for the rest of your life? Do you want to end up like a vegetable?

“At the end of the day, no one cares about you. They only care about the money you are giving them by buying it.”

Hospital seeing more cases of gas abuse

Auckland City Hospital neurology chief resident Shilpan Patel said people needed to be aware of the risks.

“Nitrous oxide inactivates vitamin B12, which means that if someone is abusing or inhaling any nitrous oxide, it lowers the amount of active B12 that they have in their body.

“When you have lower levels of B12, it means that parts of the body which are dependent on this, things like your nerves and the nerves in your spinal cord, these things can become damaged.”

In the past two years, the hospital had seen an increase in people being admitted due to abuse of the gas, Patel said.

“[Nitrous oxide-related injury] is definitely something that’s becoming more recognised, especially in the last year or two because we’ve had more presentations.

“We’ve been doing training for our neurology doctors, our emergency department doctors so that they can recognise people when they come in for nitrous oxide injury, so we can start prompt treatment.”

Despite not being addictive, the effects of the gas could influence overuse, Patel said.

“What can be addictive is the feeling of euphoria or elation and because of that people want to keep experiencing that symptom again.

“However, it’s different from substances like tobacco, which have things like nicotine in it, which cause a chemical addiction.”

Although patients could recover, rehabilitation could take time, he said.

“We’ve studied some of our patients and we’ve found that they do recover, and over time, the strength and numbness can improve.

“But in a lot of the people that we’ve been following up, they’ve taken many months to get better, and some people, six months down the line are still not back to normal.

“So, even though people do recover, it does cause significant damage and significant impairment. It’s not something that just recovers within a few days.”

Regulation, not ban, the way to go - researcher

In February this year, Students for Sensible Drug Policy Dunedin (SSDP) successfully shut down an online retailer offering 24/7 delivery of nitrous oxide to students.

They said despite not being against the recreational use of nitrous oxide, they acted because the retailer was supplying large quantities of the gas, and delivering it 24/7 to students’ houses, increasing the chance of overuse.

“Nitrous oxide is already safer than vaping, but the current lack of evidence-based regulation for recreational use is unnecessarily increasing the harm caused by this substance,” SSDP president Max Phillips said.

“It creates a space for predatory retailers to exploit people, mostly students and young people. It encourages the sale of nitrous oxide products in such large volumes they promote overconsumption, which increases the harm caused by these products.”

The lack of education around the safe use of the gas for recreational purposes prevented the creation of safer options, he said.

“Such as mandating the sale of nitrous oxide mixed with oxygen for inhalation, which would reduce the recreational effect of nitrous oxide but would massively reduce the risk of hypoxia, or the lack of oxygen provided to the brain.”

Former SSDP president and researcher Jai Whelan said banning the gas would only create a black market.

“If people want to use something, they [will] usually going to find a way to get a hold of it.

“If [nitrous oxide] becomes hyper unavailable because of restrictions, it’s likely that black market forces will come into play and try to distribute that drug in an alternative way.”

People should have the right to personal autonomy, he said.

“I think having some sort of legal regulation of the [recreational use of nitrous oxide] is a way to go. People won’t stop using it because it has become regulated, but what we can do is educate them on the harms and how to use it safely.

“We could, for example, restrict the sale to specialised stores that are R18 of course, like tobacco and alcohol. We could also sell the product only in small canisters rather than a giant tank.”

Suppliers bear responsibility - MedSafe

In a statement, MedSafe group manager Chris James said the regulator was reviewing issues around the gas supply.

“The rules around the sale of nitrous oxide in New Zealand are clear - it is illegal to supply nitrous oxide for inhalation without a prescription.

“MedSafe has previously reminded a number of companies known to sell nitrous oxide of their compliance requirements.”

MedSafe could investigate reports of nitrous oxide being sold for recreational use and take action, James said.

The agency continued to look at possible improvements to the law around the distribution or sale of nitrous oxide, he said.

“It is MedSafe’s opinion that retailers supplying recreational users bear a responsibility for the harm this activity may cause.”

- Surname has been omitted for privacy reasons

Woman loses ability to move legs after ‘nangs’ nitrous oxide overdose - NZ Herald (2024)

FAQs

Woman loses ability to move legs after ‘nangs’ nitrous oxide overdose - NZ Herald? ›

An Auckland woman who lost movement in her legs after inhaling nitrous oxide is urging the Government to regulate retail supply of the gas. Known on the streets as nangs or laughing gas, nitrous oxide has been used as a sedative for pain relief for more than 150 years, but it has also been used as a recreational drug.

Can you get paralyzed from nitrous oxide? ›

This can lead to degeneration of the spinal cord, and ultimately paralysis. “People don't tend to consider this as a risk factor, because nobody intends to become a long term or heavy user. It can seem like a bit of harmless fun, and the nickname 'laughing gas' adds to that idea.

What does nitrous oxide do to your legs? ›

Symptoms that may occur after repeated inhalation of nitrous oxide: Numbness/tingling/pain in the legs and/or arms. Muscle weakness. Permanent nerve damage.

Can nangs paralyse you? ›

This can be very painful and make walking difficult. It can even lead to paralysis, and the damage may be lasting. Regular use can stop you forming white blood cells properly. It can be hard to judge the amount to use safely.

What are the symptoms of a nitrous oxide overdose? ›

What Are Signs of Nitrous Oxide Overdose?
  • Irritation in the eyes, nose, and/or throat.
  • Wheezing or worsening cough.
  • Seizures or significant respiratory depression, which can be fatal.
  • Choking or tightness in the chest.
  • Headache, lightheadedness, or dizziness.
  • Shortness of breath (dyspnea)
  • Bluish fingers, toes, or lips.

Can nitrous oxide make you disabled? ›

Recreational use of nitrous oxide (also known as laughing gas) can lead to subacute combined degeneration of the spinal cord, a condition that can cause serious and permanent disability in young people. While it may be treated effectively if recognised early, it is commonly misdiagnosed and inappropriately treated.

Is the most common cause of death from nitrous oxide? ›

Few deaths due to inhalation of nitrous oxide are described in the literature. Accidental deaths are primarily due to recreational inhalation of the substance [12, 16–18] and autoerotic activity [19, 20]; death can occur from sudden cardiac arrhythmia or, most commonly, acute asphyxiation due to hypoxia [21].

How to reverse damage from nitrous oxide? ›

Nitrous oxide effects reversed by vitamin B12 repletion

Treating impaired metabolism of vitamin B12 first required the complete cessation of nitrous oxide use. Then, the clinicians began the repletion process, treating the patient with a seven-day course of intramuscular vitamin B12.

Is leg weakness an emergency? ›

Leg weakness always needs a doctor's evaluation as it may be due to a serious underlying condition that requires treatment. Get emergency medical care if: Your weakness is accompanied by sudden, severe pain in your back or leg. You experience loss of bladder or bowel control.

How does nitrous oxide cause peripheral neuropathy? ›

Nerve damage from nitrous oxide is thought to occur through inactivating vitamin B12, preventing the formation of myelin on nerve cells. Weekly nitrous oxide consumption correlated with increased methylmalonic acid.

Who was the girl paralyzed from nitrous oxide? ›

After a couple months, Mollie was on her way to work in a department store when she found herself unable to walk. In hospital, doctors discovered she had inflammation on her spinal cord and "massive nerve damage" from "starving" her brain of oxygen. "It was one of the doctors who said, 'do you use laughing gas?

Can nitrous oxide cause MS? ›

There is currently no evidence to support a causal link between nitrous oxide use and multiple sclerosis. There may be some conflation of the effects of the two, both resulting in damage to the lining of nerves, although this is fortunately often reversible in those who have used very large quantities of nitrous oxide.

What does nitrous oxide do to B12? ›

Neurologic symptoms associated with nitrous oxide use have been attributed to vitamin B12 deficiency. Through oxidation, nitrous oxide inactivates vitamin B12. In its inactive form, vitamin B12 is unable to function as a co-factor for methionine synthase and methylmalonyl coA mutase.

Can nitrous oxide cause brain damage? ›

Regular use or prolonged exposure to nitrous oxide may result in: memory loss. vitamin B12 depletion (long-term depletion causes brain and nerve damage)

What happens if you have too much nitrous oxide in your blood? ›

Excessive nitric oxide

Nitric oxide is released from the cerebral vasculature, brain tissue and nerve endings. It may cause headache in migraine. It may damage brain cells leading to neurodegenerative diseases like Parkinson disease, Alzheimer disease, Huntington disease and amyotrophic lateral sclerosis.

What are the four dangers of nitrous oxide toxicity and tolerance? ›

Potentially dangerous adverse effects include overdose, hypoxia, severe hypotension, unconsciousness, or death. High nitrous oxide concentrations have been associated with severe hypoxia and death from asphyxiation.

Can nitrous oxide cause spinal damage? ›

Professor Tom Warner, President of the Association of British Neurologists, said: "Recreational use of nitrous oxide carries a significant risk of damage to the nervous system, particularly the spinal cord, which is treatable if picked up.

What problems does nitrous oxide cause? ›

Side effects of N2O include transient dizziness, dissociation, disorientation, loss of balance, impaired memory and cognition, and weakness in the legs. When intoxicated accidents like tripping and falling may occur.

Can nitric oxide damage nerves? ›

Excessive local levels of NO during inflammation may damage axons and growth cones. Low-grade chronic rises in NO may also contribute toward peripheral nerve damage, or neuropathy in diabetes.

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